![]() BH has pharmacological effects like bronchodilating, antisecretory, urinary bladder relaxant, spasmolytic, hypnotic, hallucinogenic, pupil dilating, sedative and anti-diarrheal properties. All part of BH including leaves, seeds and roots contain some alkaloids such as Hyoscyamine, Atropine, Tropane and Scopolamine. It applies as a herbal medicine, but may induce intoxication accidentally or intentionally. Iranīlack henbane (BH) or Hyoscyamus niger, has been used as a medicine since last centuries and has been described in all traditional medicines. IranĤMedical Toxicology Research Centre, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, I. IranģMechanical Engineer, Hydro mechanical designer BS, Department of Dam and hydropower plant Hydromechanics of Tooss Ab Company, Mashhad, I. IranĢDepartment of Pharmacodynamy and Toxicology, School of Pharmacy, Mashhad University of Medical Science, Mashhad, I. شناسه دیجیتال (DOI): 10.22038/ajp.2014.3187Īnahita Alizadeh 1؛ Mohammad Moshiri 2؛ Javad Alizadeh 3؛ Mahdi Balali Mood * 4ġPediatrician- Fellowship of clinical Toxicology Imam Reza Hospital, Mashhad University of Medical Science, Mashhad, I. Really only safe for use in benzo-naive patients who have had known benzo-only overdose (e.g.Black henbane and its toxicity – a descriptive review.Seizure in patients relying on benzodiazepines for seizure control or who are physically dependent on benzos, or who have ingested large doses of other drugs.Suspected increased intracranial pressure.Co-ingestion of seizure-inducing agents.Suspected or known physical dependence on benzodiazepines.seizures in raised ICP, status epilepticus) Need for benzodiazepine to control potentially life-threatening condition (e.g.Hepatic dosing: no change to initial dose, reduce dose or frequency of subsequent doses. ![]() Lactation risk: Infant risk cannot be ruled out.Max total dose 0.05mg/kg or 1mg (whichever is lower) ![]()
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